Yes, ViceVersa PRO is fully compatible with Windows Server 2016.
ViceVersa PRO is fully compatible with all editions of Windows Server 2016 (Essentials, Standard, Datacenter, etc.)
ViceVersa PRO requires Windows Server 2016 with Desktop Experience installed. It does not run just on Server Core as it needs the GUI to be available.
ViceVersa PRO can be easily setup to run as a Windows Service using the VVEngine add-on.